Table 3.

Prognostic analyses of risk factors for overall survival

	Univariate analysis			Multivariate analysis
Variables	HR	95% CI	P-value	HR	95% CI	P-value
Male	3.98	2.44 − 6.45	<0.001	3.16	1.88 − 5.31	<0.001
Age ≥ 70 years	3.54	1.98 − 6.33	<0.001	2.15	1.18 − 3.93	0.012
Ever-smokers	3.41	2.12 − 5.46	<0.001
Respiratory diseases	3.76	2.38 − 5.95	<0.001
Diabetes mellitus	2.50	1.45 − 4.30	<0.001
Malignancya	3.25	2.05 − 5.14	<0.001	1.98	1.23 − 3.18	0.005
Neurological diseases	2.13	1.15 − 4.30	<0.001
Chronic renal diseases	2.92	0.92 − 9.29	0.07
BMI <18.5 kg/m2	2.34	1.48 − 3.71	<0.001	2.12	1.29 − 3.48	0.003
Lymphocytes <1000/μL	4.30	2.73 − 6.77	<0.001	2.36	1.47 − 3.78	<0.001
Hb <10.0 g/dL	2.30	1.21 − 4.36	0.011
Alb <3.5 g/dL	6.66	4.19 − 10.6	<0.001	3.93	2.42 − 6.40	<0.001
CRP ≥1.0 mg/dL	4.28	2.71 − 6.76	<0.001
FC pattern	2.87	1.65 − 5.00	<0.001	1.96	1.10 − 3.52	0.024

95% CI 95% confidence interval, HR hazard ratio, BMI body mass index, Hb hemoglobin, Alb albumin, CRP C-reactive protein, FC fibrocavitary disease

^aMalignancy included lung cancer