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. 2017 Jun 19;15:144. doi: 10.1186/s12967-017-1245-1

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© The Author(s) 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Co-registration of [⁶⁸Ga]NODAGA-RGD and [¹⁵O]water PET images and definition of myocardial contours. a and f demonstrate [⁶⁸Ga]NODAGA-RGD images during the first 2 min after injection of the tracer, b and g demonstrate the fusion of [¹⁵O]water PET images (c, h) and [⁶⁸Ga]NODAGA-RGD images used in the co-registration (a, f). Yellow lines represent myocardial contours defined in [¹⁵O]water PET images and copied to the [⁶⁸Ga]NODAGA-RGD images. d and i demonstrate the fusion of the [¹⁵O]water PET images (c, h) and [⁶⁸Ga]NODAGA-RGD images during the last 20 min of the imaging session (e, j) that demonstrate higher activity in the ischemic area in the anteroseptal wall as compared with the remote myocardium in the inferoposterior wall