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. 2017 Jun 19;14:14. doi: 10.1186/s12979-017-0096-1

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© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — Phosphorylation of ERK in T cells subsets from healthy individuals (HI) and end stage renal disease (ESRD) patients. Phosphorylation of ERK in (a) CD4⁺, (b) CD4⁺ naive, (c) CD4⁺ central memory (CM), (d) CD4⁺ effector memory (EM), as well as (e) CD8⁺, (f) CD8⁺ naive, (g) CD8⁺ CM, (h) CD8⁺EM, (i) CD8⁺ highly differentiated effector T cells (EMRA). Dots and squares represent young (n = 13) and elderly HI (n = 11), and upward- and downward-facing triangles correspond to young (n = 12) and elderly (n = 12) patients, respectively. P value: *< 0.05; Data are given as median with interquartile range