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. 2017 Jun 19;18:124. doi: 10.1186/s12931-017-0609-7

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© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Panel (a) - Percent free of exacerbation by beta-blocker use in the Macro placebo arm at 0, 30, 60, 90 and 180 days. Panel (b) – Percent free of exacerbation by beta-blocker use in the STATCOPE trial