Table 1.
Demographics, smoking history and spirometry. No statistically significant difference between study groups in within each trial
| Macro -BB | Macro + BB | Statcope -BB | Statcope + BB | |
|---|---|---|---|---|
| N | 469 | 110 | 625 | 63 |
| Age - years (SD) | 64.6 (8.6) | 67.3 (8.0) | 62 (8.51) | 63.4 (7.9) |
| Men - N (%) | 273 (58.2%) | 75 (67.6%) | 349 (55.8%) | 35 (55.6%) |
| Race | ||||
| % Black | 16.8 | 11.7 | 20.3 | 25.4 |
| % White | 79.5 | 82.9 | 77.1 | 73 |
| Smoking History | ||||
| Pack years - mean (SD) | 59.7 (33.7) | 59.4 (28.5) | 50.0 (26.3)* | 49.1 (28.9) |
| Current Smoker - % | 22.4 | 21.6 | 30.6* | 34.9 |
| Spirometry - % | ||||
| GOLD 2 | 21.8 | 44.1 | 34.3 | 38.1 |
| GOLD 3 | 42.4 | 36 | 33.9 | 34.9 |
| GOLD 4 | 35.8 | 19.8 | 31.8 | 27 |
| FEV1 - Liters (SD) | 1.09 (0.51) | 1.31 (0.52) | 1.20 (0.57)* | 1.30 (0.62) |
| FEV1 - mean % predicted value | 38.3 | 46.8 | 41.8* | 45.8 |
| FVC - Liters (SD) | 2.61 (0.89) | 2.81 (0.79) | 2.68 (0.92) | 2.65 (0.95) |
| FVC - % predicted value | 69.4 | 74.6 | 70.7 | 70.3 |
| FEV1/FVC | 41.8 | 46.8 | 44.6 | 48.8 |
| Chronic Bronchitis - % | 44.8 | 50.5 | 48.9 | 52.5 |
* - p < 0.05 when compared with corresponding subgroup MACRO cohort