Table 5.
C-index for all outcomes
| Model | C-Index | ||
|---|---|---|---|
| Heart Failure | Atherosclerotic Events | Death | |
| Model 1=Final model without eGFR and ACR | 0.80 | 0.77 | 0.74 |
| Model 2=Model 1+eGFR and ACR | 0.81 | 0.78 | 0.77 |
| Model 2+KIM-1/Cr | 0.81 | 0.78 | 0.77 |
| Model 2+NAG/Cr | 0.81 | 0.78 | 0.77 |
| Model 2+NGAL/Cr | 0.81 | 0.78 | 0.77 |
| Model 2+LFABP/Cr | 0.81 | 0.78 | 0.77 |
Final model without eGFR and ACR includes demographics (age, sex, race/ethnicity, clinical center) and CVD risk factors (diabetes mellitus, smoking, baseline CVD, systolic and diastolic BP, body mass index, LDL, HDL, angiotensin-converting enzyme inhibitor, angiotensin receptor blocker; statin, antiplatelet agents, aldosterone antagonists). ACR, albumin-to-creatinine ratio; KIM-1, kidney injury molecule-1; Cr, urinary creatinine; NAG, N-acetyl-β-d-glucosaminidase; NGAL, neutrophil gelatinase-associated lipocalin; L-FABP, liver fatty acid-binding protein; CVD, cardiovascular disease.