Table 1.
Characteristics of Urothelial Carcinoma Patients (N=41).
Characteristics | Overall | Disease Status | P-value‡ | |
---|---|---|---|---|
Refractory* n=29 (71%) | Response† n=12 (29%) | |||
Age (years) | 66.0 (49.0–83.0) | 69.0 (47.5–82.5) | 65.0 (51.0–87.0) | 0.39§ |
Gender | ||||
Female | 16 (39.0) | 9 (31.0) | 7 (58.3) | |
Male | 25 (61.0) | 20 (69.0) | 5 (41.7) | 0.16 |
Tumor Stage | ||||
pTa | 12 (29.3) | 8 (27.5) | 4 (33.3) | |
pTis | 15 (36.6) | 10 (34.5) | 5 (41.7) | |
pT1 | 13 (31.7) | 10 (34.5) | 3 (25.0) | |
T1 | 1 (2.4) | 1 (3.5) | 0 (0) | 0.88 |
Tumor Grade | ||||
Non-invasive | 28 (68.3) | 18 (62.1) | 10 (83.3) | |
Invasive | 13 (31.7) | 11 (37.9) | 2 (16.7) | 0.28 |
Tumor Architecture | ||||
Flat | 22 (53.7) | 16 (55.2) | 6 (50.0) | |
Papillary | 19 (46.3) | 13 (44.8) | 6 (50.0) | 1.0 |
Prior history of BCG therapy|| | ||||
No | 22 (53.7) | 11 (37.9) | 11 (91.7) | |
Yes | 19 (46.3) | 18 (62.1) | 1 (8.3) | 0.002 |
Smoking | ||||
Never | 13 (31.7) | 10 (34.5) | 3 (25.0) | |
Ever | 28 (68.3) | 19 (65.5) | 9 (75.0) | 0.72 |
Refractory Disease Status: Patients with No response to therapy.
Response Disease Status: Patients with no evidence of disease for at least 2 years after one cycle of BCG.
Fishers exact test.
Wilcoxon rank sum test.
Prior history of BCG therapy: Bacillus Calmette-Guerin (BCG) treatment before admittance to Memorial Sloan Kettering Cancer Center (MSKCC).