Table 5.
In vitro α-amylase inhibition of Cynara scolymus leaves extract and acarbose commercial drug
Sample | Concentration (μg/mL) | % Inhibition | IC 50 (μg/mL) |
---|---|---|---|
Acarbose | 50 | 31.05 ± 0.08 | 14.83 |
100 | 67.40 ± 0.59 | ||
200 | 90.35 ± 0.31 | ||
Hexane | 50 | 17.46 ± 0.05 | - |
100 | 25.63 ± 0.19 | ||
200 | 30.11 ± 0.28 | ||
Ethylacetate | 50 | 29.90 ± 0.86 | - |
100 | 33.79 ± 1.20 | ||
200 | 47.50 ± 1.43 | ||
Butanol | 50 | 53.09 ± 0.88 | 82.19 |
100 | 60.83 ± 1.02 | ||
200 | 79.08 ± 0.97 | ||
Ethanol | 50 | 50.18 ± 0.58 | 72.22 |
100 | 69.23 ± 0.84 | ||
200 | 83.71 ± 0.77 | ||
Aqueous | 50 | 46.91 ± 1.27 | 95.78 |
100 | 52.20 ± 0.99 | ||
200 | 66.24 ± 1.13 |
Values are given as means ± S.D. (n = 3)