Table 7.
Effect of Cynara scolymus leaves extracts on hematological parameters of experimental groups of rats
| Groups of treatment | Cont | Diab | Diab + Ethanol extract of leaves C. scolymus (200 mg/kg) | Diab+ + Ethanol extract of leaves C. scolymus (400 mg/kg) | Diab + Acarbose (12 mg/kg) |
|---|---|---|---|---|---|
| RBC (×106) | 6.88 ± 1.31 | 5.08 ± 1.80*** | 7.32 ± 0.70###£ | 7.50 ± 0.80### | 7.66 ± 0.30### |
| Hb (g/dl) | 13.00 ± 0.60 | 9.64 ± 3.37*** | 12.54 ± 0.95###£££ | 13.7 ± 0.89### | 13.86 ± 0.58### |
| MCV (fl) | 60.40 ± 4.30 | 57.00 ± 2.86*** | 58.40 ± 3.00###£££ | 47.53 ± 0.89###£ | 60.80 ± 2.68### |
| MCH (pg) | 20.00 ± 4.47 | 19.10 ± 1.46ns | 18.60 ± 1.14###£ | 18.22 ± 0.41### | 18.00 ± 0.45### |
| MCHC (g/dl) | 32.6 ± 5.27 | 16.87 ± 0.25*** | 28.53 ± 1.37###£ | 29.60 ± 1.14###£ | 30.00 ± 0.71### |
| WBC (×103/ul) | 8.22 ± 0.93 | 5.30 ± 0.70*** | 5.2 ± 0.35£££ | 6.4 ± 0.53#£££ | 8.26 ± 0.34### |
| PLT (×103 /ul) | 900 ± 0.63 | 260 ± 0.34*** | 705 ± 0.45###£ | 605 ± 0.87### | 640 ± 0.54### |
Diabetic rats were orally administered with the ethanol extract from leaves of C. scolymus and acarbose at the doses mentioned earlier for 28 days. Values are given as means ± SD (n = 8). *** p ≤ 0.001 were considered significant compared to control group; # p ≤ 0.05, ### p ≤ 0.001 were considered significant compared to diabetic rat.; £ p ≤ 0.05, £££ p ≤ 0.001 compared to diabetic rats treated with acarbose; ns: non-significant changes between diabetic treated groups vs. normal control group after 28 days treatment. RBC Red blood cells, Hb Hemoglobin, MCV Mean corpuscular volume, MCH Mean corpuscular hemoglobin, MCHC Mean corpuscular concentration, WBC White blood cell, PLT Platelet count