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. 2017 Jun 19;10:37. doi: 10.1186/s13048-017-0336-1

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© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — Whole-mount in situ detection of miR-130b expression in oocytes (immature COCs, mature COCs) and preimplantation embryos. The red color indicates the expression level of miR-130b or scramble miRNA probe, while the blue color indicates nuclear staining using 4′,6-diamidino-2-phenylindole (DAPI). The 2D and 3D indicate the two and three dimension images, respectively. COCs; cumulus oocyte complexes