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. 2017 Jun 19;10:37. doi: 10.1186/s13048-017-0336-1

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© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 5 — The mRNA abundance level of SMAD5 and MSK1 genes in (a) immature oocytes (IMO), mature oocytes (MO), immature cumulus (IMCC), mature cumulus cells (MCC), granulosa cells (GC) (a), and preimplantation stage embryos (b). Bars with different letters are statistically significant (p < 0.05). The bars graphs represent the mean ± standard deviation (SD) and the data was analyzed from three independent biological samples of MO, IMO IMCC, MCC, zygotes; 2-cell, 4-cell, and 8-cell stage embryos; morula; and blastocysts