Fig. 4.

Putative structural rearrangement of the FGFR2 genomic region in the right metastasis. Barcode and read-based evidence indicate the likely occurrence of events was a 30-Mb deletion event with a nearby inversion event, and an inversion event with a deletion at the boundary; the resulting rearrangement then underwent an approximately ninefold tandem duplication. Barcode analysis indicates that all of these events are in cis with one another and thus occurred on only one copy of chromosome 10