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. 2017 Jun 19;18:123. doi: 10.1186/s12931-017-0610-1

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© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — FOT respiratory mechanics parameters at baseline. Central airway resistance, R_n (a), tissue damping, G (b), tissue elastance, H (c) and tissue hysteresivity G/H (eta) (d) were measured using a prime-8 perturbation. Parameters are shown for each individual mouse, along with group means. * p < 0.05 and *** p < 0.001 compared to the naive control group. n = 7 –8 per group