Table 2.
The Published Dynamic Turnover Times for Popular FA Proteins
| Protein Name | FRAP t1/2(s) | Cell Type |
|---|---|---|
| Vinculin | 1.9/14/50/11/21 | HelaJW53/MEF54, 55/REF5256 |
| Paxillin | 1.5/25/17.7/53.2/20 | HelaJW53/MEF55/Bovine capillary endothelial cells57/MEF, TIRF FRAP58/REF5256 |
| FAK | 2.1/7/6.7/14 | HelaJW53/MEF55/Bovine capillary endothelial cells57/REF5256 |
| Zyxin | 0.5/12/7/10 | HelaJW53/MEF55/REF5256 |
| Talin | 2.2/23/77/18 | HelaJW53/MEF55/Bovine capillary endothelial cells57/REF5256 |
| ILK | 9.2/12 | HelaJW53/REF5256 |
| α‐actinin | 36/14.1/27 | MEF55/Bovine capillary endothelial cells57/REF5256 |
| beta3‐Integrgin | 38.5 | Bovine capillary endothelial cells57 |
| p130Cas | 5.8/14 | MEF, TIRF FRAP58/REF5256 |
| Tensin | 55 | REF5256 |
| Src/CSK | 9 | REF5256 |
| Pinch | 14 | REF5256 |
| VASP | 0.7/15 | HelaJW53/REF5256 |
Notice that FRAP (Fluorescence Recovery After Photobleaching) results may vary between different microscopy systems, cell types, focal adhesion status, and based on other factors. Different FRAP results and cell types have been referenced respectively.