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Improved angiogenesis and fibrosis of rat hearts after transplantation with SRT1720 pretreated aged hMSCs. Blood vessels in the border zone of ischemic hearts were stained with α-SMA (a and b) and CD31 (c and d). Cardiac remodeling was analyzed by Masson's trichrome staining (e and f). Data are expressed by mean±S.D. (N=6). *P<0.05 versus DMSO group; **P<0.01 versus DMSO group; #P<0.05; ##P<0.01
