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Caspase 3-mediated Beclin 1 cleavage in STS-treated PC12 cells. (a) Cells were treated with STS, STS+CasI, STS+Cas3I, CasI or Cas3I. The protein expression of Beclin 1, LC3 and GAPDH was evaluated by western blotting. (b) Relative protein expression (interested protein/GAPDH) was quantified. Data were calculated from five independent experiments. *P<0.05 versus Ctrl; #P<0.01 versus STS
