Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2017 Apr 6;8(4):e2738. doi: 10.1038/cddis.2017.161

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2017 The Author(s)

Cell Death and Disease is an open-access journal published by Nature Publishing Group. This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article's Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

PMC Copyright notice

Nuclear translocation of Beclin 1 in damaged neurons. (a) Cells were treated with STS, STS+Spd or Spd. After incubation, cells were stained with anti-Beclin 1 N terminal (BN) or C-terminal (BC) antibody. The nuclei were counterstained with Hoechst 33342. Scale bar, 10 μm. Curves indicated the colocalization between Beclin 1 (green) and Hoechst (blue) and correlated to the lines drawn in the enlarged images. The x axis represented the distance (inches) along the line and the y axis indicated the pixel intensity. (b) Hippocampal CA1 and cortical areas were obtained from 12-month-old PS1/APP (AD) mice (n=6) and age-matched WT control (n=6). Brain slides were immunostained with anti-Beclin 1 N terminal antibody and the nuclei were counterstained with hematoxylin. Scale bar, 20 μm