Figure 1.

The expression of TBK1 and RGC senescence after acute IOP elevation-induced ischemic retinas in vivo. (a) Representative β-gal staining images of frozen retinal slice after acute IOP elevation-induced ischemic injury. (b) Representative β-gal staining images of retina flat after IOP elevation-induced ischemic injury. (c) Statistical analysis of the data shown in (b). The data are expressed as the means±s.e.m. from three independent experiments. **P<0.01 versus control. (d) Western blot showing TBK1, p16 and cyclin A expression in ischemic retina. (e-g) Statistical analysis of the data shown in (d). The data are expressed as the means±s.e.m. from three independent experiments. *P<0.05 versus control and **P<0.01 versus control. (h) Representative images of TBK1 and p16 expression in ischemic retina slice