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. 2017 Apr 20;8(4):e2752. doi: 10.1038/cddis.2017.169

Figure 5.

Figure 5

The effect of PFT-α on p16 expression and cell senescence after TBK1 overexpression. (a) Western blot showing the effect of p53 inhibitor PFT-α (20 μM) on p16 and cyclin A expression after TBK1 overexpression in HEK293. (b-d) Statistical analysis of the data shown in (a).The data are expressed as the means±s.e.m. from three independent experiments, *P<0.05 versus control. (e) Representative β-gal staining images showing the effect of PFT-α on cell senescence after TBK1 overexpression in HEK293