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. 2017 Apr 6;8(4):e2739. doi: 10.1038/cddis.2017.61

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Copyright © 2017 The Author(s)

Cell Death and Disease is an open-access journal published by Nature Publishing Group. This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article's Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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miR-10a is overexpressed in primary CRC cells and tissues. (a) The miRNAs differentially expressed between SW480 and SW620 cells were analyzed using a miRNA microarray. The five miRNAs exhibiting the significant differences are shown. The miRNAs with a signal background ratio of 1.5 or greater were considered to represent positive expression (+), and the others were considered to represent negative expression (−). (b) RT-qPCR results of the five miRNAs in SW480 and SW620 cells (*P<0.05). (c) RT-qPCR results of miR-10a in human primary CRC tissues (CA) and paired lymph node metastases (M). The expression levels were normalized to U6 snRNA (*P<0.05, **P<0.01, NS, not significant)