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. 2017 Apr 6;8(4):e2735. doi: 10.1038/cddis.2017.90

Figure 3.

Figure 3

IL-33 is essential for MC903-induced AD. (a) Ear thickness of BL6 and IL-33−/− mice after daily MC903 treatment. (b and c) Clinical score of the ear redness and scaling (b) and H&E staining (c) of the ear and of BL6 and IL-33−/− mice treated with ethanol or MC903 at day 12. Scale bar represents 50 μm. (d-g) The protein expression of eotaxin-2 (d), IL-4(e), IL-5 (f) and IL-13 (g) in the ear of BL6 and IL-33−/− mice treated with ethanol or MC903 at day 12. *P<0.05,**P<0.01,***P<0.001. P-values were analyzed by two-way ANOVA in a and one-way ANOVA in b-g. All data are representative of two to three independent experiments with n=4–8 per group and are means±S.E.M.