Figure 1.

Mesenchymal stromal cells induce the differentiation of bone marrow mononuclear cells into myeloid cells. BM MNC were cultured alone or with MSC (ratio 5:1) for 4 days. (A) Proportion of CD11b⁺Gr-1^high and CD11b⁺Gr-1^low-neg cells in the live gate. A typical result of ten independently performed experiments is shown. (B) Percentage of Gr-1^high and Gr-1^low-neg cells in CD11b⁺ cells. Mean of ten independent experiments, ± SEM. *** P<0.001 **** P<0.0001 unpaired t test. (C) Absolute number of CD11b⁺ cells recovered from initial seeding from BM cultured alone (white bars) or with MSC (black bars) for 4 days. Mean of ten independent experiments, ± SEM **P<0.005, unpaired t test.