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. 2017 May;102(5):854–864. doi: 10.3324/haematol.2016.153528

Figure 4.

Figure 4.

Time to in vivo engraftment and mouse survival correlate with molecular risk group stratification of the transplanted acute myeloid leukemia. (A) Favorable-risk AML showed longer time to engraftment when compared to intermediate- or adverse-risk AML. (B) Kaplan-Meier survival analysis of 99 mice transplanted with human AML indicates that mouse survival depends on the AML molecular risk group. Note that animals transplanted with favorable-risk AML cases showed the longest survival. (black: favorable, n=4; blue: intermediate (I+II), n=8; red: adverse risk AML, n=3). See Table 1 for transplanted/engrafted mouse numbers per individual AML case. A log-rank (Mantel-Cox) test was applied to calculate statistical significance.