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. Author manuscript; available in PMC: 2018 Jun 14.
Published in final edited form as: Neuroscience. 2017 Apr 10;353:76–86. doi: 10.1016/j.neuroscience.2017.04.001

Figure 5.

Figure 5

The diversity of cold, menthol, and AITC responses from HEK293 cells stably expressing either human TRPA1 or TRPM8 channels. The experimental protocol is identical to that described in the Figure 1 legend. (A) Representative traces from human TRPA1-expressing HEK cells. A subset responded to cold, menthol and AITC (47.2% ± 2.2%). Another subset responded to menthol and AITC (34.0% ± 2.1%). An additional subset only responded to AITC (14.8% ± 1.6%). See summary in Table 1. (B) Representative traces from human TRPM8-expressing HEK cells. A subset of these neurons responded to 18 °C and 4 °C bath applications, and menthol (89.8% ± 1.0%). Another subset only responded to 4 °C and menthol (9.2% ± 1.0%). See summary in Table 1. (C) Representative trace from untransfected HEK cells.