Skip to main content
. 2016 Jul 28;8(4):391–402. doi: 10.1080/21505594.2016.1213472

Table 1.

Studies of carbapenem-resistant Klebsiella pneumoniae in solid organ transplant recipients.

Reference Geographic Location Incidence of Post-Transplant CRE Infection Median Time from Transplant to CRE Infection Type of Infectiona Mortality Rate
Heart Transplants          
20 Brazil 16.7% (2/12) 90 days Bacteremia: 50% Pneumonia: 50% 50% (30-day)
Lung Transplants          
21b Pittsburgh 0.4% (2/546) 218 days Bacteremia: 100% 0% (30-day)
22 Israel 5.9% (8/136) 27 days Pneumonia: 38% UTI: 25% Bacteremia: 25% 88% (overall)
Liver Transplants          
20 Brazil 12.9% (4/31) 16 days Bacteremia: 100% Pneumonia: 25% 25% (30-day)
21b Pittsburgh 1.3% (8/610) 24 days Bacteremia: 100% Pneumonia: 50% 25% (30-day)
23 New York City 8% (14/175) 12 days Bacteremia: 86% Peritonitis: 79% 71% (overall)50% (30-day)
31b Greece NR (17 cases) 13 days Bacteremia: 100% 82% (ICU mortality)
24 New York City 6.6% (20/304) 11 days SSI/intra-abdominal: 65% Bacteremia: 55% 45% (overall)
95 Italy 8.4% (20/237) 42 days Bacteremia: 90% Pneumonia: 30% 45% (180-day)
Kidney Transplants          
25 Brazil 1.9% (21/1101) 49 days SSI: 48% Bacteremia: 39% 42% (30-day)
20 Brazil 26.3% (5/19) 17 days UTI: 60% Bacteremia: 60% 60% (30-day)
26 Argentina 13.3% (6/45) 36 days UTI: 83% Bacteremia: 17% 33% (overall)
27c New York City 1.1% (20/1852) 47 days Bacteriuria: 100% 30% (overall)
28 New York City 2.5% (13/522) 185 days UTI: 69% Bacteremia: 38% 46% (overall)
30 Italy NR (8 episodes) NR UTI: 100% Bacteremia: 100% 0% (30-day)
Intestinal Transplants          
21b Pittsburgh 5.4% (6/112) 209 days Bacteremia: 100% 33% (30-day)

Notes. Abbreviations: CRE, carbapenem-resistant Enterobacteriaceae; UTI: urinary tract infection; NR, not reported; ICU, intensive care unit; SSI, surgical site infection

a

The 2 most common sites of infection are listed

b

The study evaluated episodes of CRE bacteremia only

c

The study evaluated episodes of CRE bacteriuria only