Table 1.
Recapitulative informations on propolis from Adamawa Region, Cameroon
| Propolis samples (Year) | Solvant of extraction (Yield) | Phytochemical constituent | Biological activities | References |
|---|---|---|---|---|
| Propolis Meiganga (2003 & 2005) | Ethanol (3.27%) | Detection of phenolic compounds with HPLC-PDA | Antibacterial activity against gram positive bacteria. Relation between phenolic compounds amount and antibacterial activity. | [21, 24] |
| Propolis Meiganga (2006) | Methanol (3.7%) | lup-20(29)-en-3-one, lupeol, erythrodiol palmitate, 18-iso-olean-12-ene-3,11-dione, Caffeic acid phenethyl ester (CAPE) | Antinociceptive activity of all the three pentacyclic triterpenoids in the test models of chemical nociception and mechanical hypernociception | [26] |
| Propolis Meiganga (2008) | Hexane (44.8%) | Alkaloids, Coumarins, Steroids, Triterpenes, Volatile, 2 compound was not yet elucidated | Absence of antibacterial activity | [27] |
| Propolis Meiganga (2008) | Methanol (3.5%) | Alkaloids, Reducing compounds, Coumarins, Flavonoids, Saponins, Tannins | Antibacterial activities; It was active against Escherichia coli and Pseudomonas aeruginosa (MIC: 0.2 mg/ml) | [27] |
| Propolis Adamawa (2013) | Acetone and methanol (70%) | Terpenoids, phenolic acids, ursolic acid, β-amyrin, Prenylated phloroglucinone, cycloartenol acetate | Phlorogucinonone was found to possess the highest potency against Trypanosoma brucei brucei | [52] |
| Propolis Adamawa (2007) | Ethanol (missing data) | Missing data | Among all African propolis sample tested, Cameroonian propolis was the most potent. | [25] |
| Propolis Ngaoundal (2011) | Ethanol (5.25%), methanol (9%) and water (1.5%) | Volatile oils, Phenolic compounds, Saponins, Reducing substances, Coumarines, Flavonoids, Triterpenes, Catechic tannins, Fatty acids. | All extracts contain phenolic compounds and present antiradical activities Antioxidant capacities: the order of decreasing antiradical activity is Water > Methanol > Ethanol | [26] |
| Propolis Ngaoundere (2004) | Ethanol (missing data) | Total polyphenols (mg/L) 10.99 ± 2.56; Tannins (mg/L): 1.57 ± 1.62 | The Cameroonians propolis exhibited higher scavenging (antiradical activity (%):83.4 ± 2.3); activity which could justify their commercialisation and role in the management of some chronic diseases | [23] |
| Propolis Ngaoundere (2003) | Ethanol (missing data) | Total polyphenols (mg/L) 227.8 ± 36.0; Tannins (mg/L): 16.3 ± 12.6 (PROMAX-C, 2003) Total polyphenols (mg/L) 772.8 ± 270.2; Tannins (mg/L): 453.8 ± 361.5 in PROMAX-C of 2006 |
All PROMAX-C samples tested showed evidence of radical scavenging properties with values ranging from 28 to 70%. Radical scavenging activity: Antiradical activity (%):43.7 ± 13.8 for PROMAX-C made in 2003 and Antiradical activity (%):67.3 ± 3.0 for PROMAX-C made in 2006. | [23] |
| Propolis Meiganga (2005) |
Ethanol (4%) | Contains phenolic compounds | Antibacterial activity against gram positive bacterial strain tested except Enterococcus faecalis | [21] |
| Propolis Martap (2005) |
Ethanol (3.5%) | Most active than PROMAX-C from Meiganga with a most higher phenolic content | Antibacterial activity against gram positive bacterial strain tested except Enterococcus faecalis. This propolis was the most active and content more phenolic compounds than other tested propolis. | [21] |