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. 2017 Apr 18;6(2):124–133. doi: 10.1080/21623945.2017.1320002

Table 1.

Differentially methylated regions in epididymal and inguinal adipocytes from diet-induced and ob/ob mice. Proportion of hyper- and hypo-methylated regions and number of genes mapped within the +/−10kb region of the DMRs. DMRs: Differentially methylated regions. DIO: Diet-induced obese.

Origin of isolated mature adipocytes Number of DMRs (p-value <0.001) as compared with lean mice Number of Hypermethylated regions (obese > lean) Number of Hypomethylated regions (lean > obese) Number of genes mapped by DMRs
Epididymal tissue from DIO mice (n = 3) 5393 512 4881 3013
Epididymal tissue from ob/ob mice (n = 4) 773 0 773 318
Inguinal tissue from DIO mice (n = 3) 4606 1 4605 2603
Inguinal tissue from ob/ob mice (n = 4) 146 15 131 57