Table 1.
Characteristics of the exposed and unexposed cohorts. The exposed cohort was divided according to number of redeemed prescriptions of selective serotonin-reuptake inhibitors (SSRI’s): minimum of one prescription, limited to one prescription, and minimum two prescriptions. Total number of children, n = 1.256.317
| SSRI prescriptions redeemed a minimum of one time (n = 19,807) | SSRI prescriptions redeemed one time only (n = 11.351) | SSRI prescriptions redeemed minimum two times (n = 8.456) | No prescriptions of SSRIs (n = 1.236.510) | |
|---|---|---|---|---|
| Maternal age | ||||
| ≤19 | 308 (1.6%) | 184 (1.6%) | 124 (1.5%) | 18.039 (1.5%) |
| 20–24 | 2.645 (13.4%) | 1.530 (13.5%) | 1.115 (13.2%) | 145.031 (11.7%) |
| 25–29 | 5.764 (29.1%) | 3.234 (28.5%) | 2.530 (29.9%) | 415.536 (33.6%) |
| 30–34 | 6.678 (33.7%) | 3.779 (33.3%) | 2.899 (34.3%) | 437.740 (35.4%) |
| ≥35 | 4.412 (22.3%) | 2.624 (23.1%) | 1.788 (21.1%) | 220.164 (17.8%) |
| Maternal smoking status | ||||
| No | 13.384 (67.6%) | 7.838 (69.1%) | 5.546 (65.6%) | 946.853 (76.6%) |
| Yes | 5.656 (28.6%) | 3.095 (27.3%) | 2.561 (30.3%) | 186.807 (15.1%) |
| Missing | 767 (3.9%) | 418 (3.7%) | 349 (4.1%) | 102.850 (8.3%) |
| Sex of child | ||||
| Male | 10.249 (51.7%) | 5.862 (51.6%) | 4.387 (51.9%) | 601.949 (48.7%) |
| Female | 9.558 (48.3%) | 5.489 (48.4%) | 4.069 (48.1%) | 634.561 (51.3%) |
| Parity | ||||
| 1 | 8.792 (44.4%) | 4.912 (43.3%) | 3.880 (45.9%) | 545.646 (44.1%) |
| >1 | 11.015 (55.6%) | 6.439 (56.7%) | 4.576 (54.1%) | 690.864 (55.9%) |
| Birth year | ||||
| 1996–2001 | 1.972 (10.0%) | 1.033 (9.1%) | 939 (11.1%) | 387.716 (31.4%) |
| 2002–2007 | 6.077 (30.7%) | 2.976 (26.2%) | 3.101 (36.7%) | 376.939 (30.5%) |
| 2008–2011 | 6.787 (34.3%) | 3.952 (34.8%) | 2.835(33.5%) | 240.952 (19.5%) |
| 2012–2016 | 4.971 (25.1%) | 3.390 (29.9%) | 1.581 (18.7%) | 230.903 (18.7%) |