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. Author manuscript; available in PMC: 2018 May 1.
Published in final edited form as: Lancet Neurol. 2017 Mar 20;16(5):351–359. doi: 10.1016/S1474-4422(17)30056-X

Figure 2.

Figure 2

Regional DASB Binding

A: Group mean DASB binding potential in different volumes of interest (by reference tissue model); *age-adjusted ANCOVA significantly different; hypothalamus, p<0.0001; striatum, p=0·017; brainstem, p=0·014, corrected for multiple comparisons; whiskers indicate standard deviation.

B: Absolute difference between group mean (bars) and healthy control mean (blue line) in each region

C: Relative difference between healthy control mean (blue line) and binding potential for each participant (as a proportion of the mean healthy control value) in that region