Table 3.

DTBZ and DASB binding per group in Study 2

Group	DASB BP–Cortex (mean, sd)	DASB BP–Striatum (mean, sd)	DASB BP–Brainstem (mean, sd)	DASB BP–Hypothalamus (mean, sd)	DTBZ–putamen (mean, sd)*
HC	0·43 (0·10)	1·61 (0·21)	2·14 (0·51)	1·90 (0·40)	-
LRRK2-U	0·55 (0·10)	1·70 (0·23)	2·36 (0·43)	2·55 (0·49)	1·04 (0·28)
LRRK2-PD	0·38 (0·09)	1·41 (0·14)	1·86 (0·26)	1·87 (0·35)	0·30 (0·11)
sPD	0·41 (0·15)	1·35 (0·30)	2·07 (0·33)	2·01 (0·33)	0·25 (0·11)

HC= healthy control; LRRK2-U= unaffected mutation carrier; LRRK2-PD= affected mutation carrier; sPD = sporadic PD

^*DTBZ data are expressed as a left/right average normalized to age-matched healthy control values