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| Recommendation for Chelation Therapy | ||
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| COR | LOE | Recommendation |
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| III: No Benefit | B-R | Chelation therapy (eg, ethylenediaminetetraacetic acid) is not beneficial for treatment of claudication.204 |
|
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| See Online Data Supplement 27. | In a Cochrane review of 5 studies with 260 participants, chelation therapy showed no significant difference in symptoms (maximal and pain-free walking distance) compared with placebo.204 | |
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