|
Recommendation for
ALI Medical Therapy |
|
COR |
LOE |
Recommendation |
|
I |
C-EO |
In patients with ALI, systemic
anticoagulation with heparin should be administered unless
contraindicated. |
|
N/A |
Heparin (generally intravenous
unfractionated heparin) is given to all patients acutely.35,364 This can stop thrombus
propagation and may provide an anti-inflammatory effect that lessens
the ischemia. Patients who have received heparin before the onset of
ALI and have a decrease in platelet count may have heparin-induced
thrombocytopenia.365,366 In this situation, a direct thrombin inhibitor
is given, rather than heparin, if heparin-induced thrombocytopenia
with thrombosis is suspected. |
|