Fig. 1.

Gene map of the signaling pathways of the Toll-like receptor, activation of complement and interaction of cytokines (shown only partly) derived from the KEGG database. Genes showing significantly different expression in the CoPS-3/4 vs. H groups are marked with red asterisks. The figure shows the dependence of complement activation and cytokine pathways on the Toll-like receptor pathway (red arrows). Differentially expressed genes are located on the paths leading to the complement and cytokine pathways