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. 2016 Aug 8;34(34):4094–4101. doi: 10.1200/JCO.2016.67.5066

Fig 2.

Fig 2.

Mean plasma selinexor concentration in pediatric patients at day 1 showed little separation between the 30 and 40 mg/m2 dose levels, with an increase in exposure evident at the 55 and 70 mg/m2 dose levels. Mean plasma selinexor concentration in pediatric patients after the day-22 dose showed peak levels and dynamics similar to the day-1 levels.