Fig 1.
(A) Stage IIIC disease. (B) Stage IV disease. Use of neoadjuvant chemotherapy (NACT) increased significantly over time (Ptrend < .001 for both groups). Intraperitoneal and intravenous (IP/IV) chemotherapy is shown for comparison. Three patients with stage IIIC disease and one with stage IV who were diagnosed in 2003 are included in the estimate for 2004. Twenty-three patients with stage IIIC disease and seven with stage IV who were diagnosed in 2012 are included in the estimate for 2011. PCS, primary cytoreductive surgery.