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(A) Effect of 10 μM cadmium exposure for 24 h on wild type (pmtl-1::GFP) and two C. elegans stains containing mutant alleles of atf-7 (pmtl-1::GFP;atf-7(gk715) and pmtl-1::GFP;atf-7(mt15)) on GFP expression. (B) atf-7 gene x cadmium interaction factors were determined by comparing changes in mtl-1 mRNA levels after exposure to 100 μM cadmium for 1 (dark gray) h or 5 (light gray) h. * p < 0.05.
