Fig 3.
Renal function studies using creatinine clearance (CCr, panel A), fractional sodium excretion (FENa+, panel B), proximal (FEPNa+, panel C) and post-proximal (FEPPNa+, panel D), fractional sodium excretion and fractional potassium excretion (FEK+, panel E), in male 10-week-old and 16-week-old NP and LP offspring compared with age-matched NPDNx and LPDNx groups (n = 10 animals for each group). Results are expressed as median and quartile deviation. Data were analyzed using nonparametric analysis by Kruskal–Wallis test with post hoc Bonferroni’s contrast test. The level of significance was set at *P ≤ 0.05, **P ≤ 0.01 or **P ≤ 0.001.