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. 2017 Jun 20;12(6):e0179509. doi: 10.1371/journal.pone.0179509

Table 2. The effects of TMZ treatment on lean male hearts subjected to AHF (n = 6).

Treatment group Heart rate (%) Sig. LVDevP (%) Sig.
Control 210.13 ± 127.11 ns 1259.06 ± 485.90 **
***
TMZ at CAHF 28.26 ± 1.48 2204.29 ± 355.33
TMZ at RAHF 29.74 ± 2.23 6025.70 ± 654.65
Treatment group LVEDP (%) Sig. LVESP (%) Sig.
Control 201.85 ± 36.57 ns 211.06 ± 43.49 ns
TMZ at CAHF 160.23 ± 9.38 170.36 ± 11.07
TMZ at RAHF 158.26 ± 18.72 171.80 ± 24.07

Data represent the last ten minutes of the RAHF phase and expressed as a percentage of CAHF. Significance is expressed as **p<0.01; ***p<0.001 vs. TMZ (at RAHF). LVDevP: left ventricular developed pressure; LVEDP: left ventricular end diastolic pressure; LVESP: left ventricular end systolic pressure; CAHF: critical acute heart failure; RAHF: recovery acute heart failure; Sig.: significance; ns: not significant.