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. 2017 Jun 20;12(6):e0179509. doi: 10.1371/journal.pone.0179509

Table 10. Comparison of TMZ effects on hearts subjected to AHF—Lean males vs. lean females (follicular) (n = 6).

Control
Parameters Males Females Sig.
Heart rate
(%)
210.13 ± 127.11 30.21 ± 4.14 ns
LVDevP
(%)
1259.06 ± 485.90 2875.81 ± 725.74 ns
LVEDP
(%)
201.85 ±36.57 140.87 ± 9.40 ns
LVESP
(%)
211.06 ± 43.49 149.10 ± 10.88 ns
TMZ at CAHF TMZ at RAHF
Males Females Sig. Males Females Sig.
Heart rate
(%)
28.26 ± 1.48 27.94 ± 3.51 ns 29.74 ± 2.23 23.93 ± 2.00 ns
LVDevP
(%)
2204.29 ± 355.33 8049.63 ± 1961.21 *** 6025.70 ± 654.65 4918.75 ± 762.73 ns
LVEDP
(%)
160.23 ± 9.38 139.35 ± 24.49 ns 158.26 ± 18.72 137.35 ± 3.71 ns
LVESP
(%)
170.36 ± 11.07 152.26 ± 30.49 ns 171.80 ± 24.07 145.29 ± 4.73 ns

Data represent the last ten minutes of the RAHF phase and is expressed as a percentage of CAHF. Significance is expressed as ***p<0.001 vs. lean males. LVDevP: left ventricular developed pressure; LVEDP: left ventricular end diastolic pressure; LVESP: left ventricular end systolic pressure; CAHF: critical acute heart failure; RAHF: recovery acute heart failure; Sig.: significance; ns: not significant.