Skip to main content
. 2017 Jun 20;12(6):e0179099. doi: 10.1371/journal.pone.0179099

Fig 1. Overexpression of sgp130Fc does not impact MCD diet induced weight loss.

Fig 1

(A) Concentration of soluble gp130 Fc (sgp130Fc) transgene in plasma of mice at 3 weeks of age (B) Fasting glycemia after 4 weeks of methionine and choline deficient diet (MCDD). (C) Body mass, (D) weight change expressed as percent initial body weight (E) EchoMRI fat mass and (F) EchoMRI lean mass in control and MCDD mice over the course of dietary intervention. Data expressed as average ± SEM, n = 6–7. Statistical analysis by 2 way ANOVA, ***p<0.001 Main effect for Control vs MCDD; # p<0.05 Main effect for WT vs sgp130Fc Tg.