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. 2017 Jun 20;12(6):e0179099. doi: 10.1371/journal.pone.0179099

Fig 3. Sgp130Fc transgenic mice develop a similar NASH pathology to wild type mice on a MCD diet.

Fig 3

Liver condition in 4 weeks fed control and methionine and choline deficient diet (MCDD) mice was assessed by studying (A) liver weight (expressed as % body weight), (B) liver enzymes ALT and AST, (C) liver histology with H&E staining and (D) intra-hepatic cholesterol concentrations. Data expressed as average ± SEM, n = 6–7. Statistical analysis by 2 way ANOVA, ***p<0.001 Main effect for Control vs MCDD; & p<0.05 for diet/genotype interaction.