Table 2. Wolbachia proteins differentially expressed in CLas+ ACP guts.
| Protein Annotation1 | Protein GI2 | Protein Accession3 | Log2 Fold Change CLas+/-4 | P Value5 |
|---|---|---|---|---|
| iron deficiency-induced protein A | gi|516101257 | WP_017531837.1 | -3.170 | 0.033 |
| Ankyrin | gi|516101663 | WP_017532243.1 | -3.044 | 0.047 |
| membrane protein | gi|516101883 | WP_017532463.1 | -2.833 | 0.01 |
| polynucleotide phosphorylase | gi|516101360 | WP_017531940.1 | -2.617 | < 0.00010 |
| 50S ribosomal protein L1 | gi|516101535 | WP_017532115.1 | -2.585 | 0.027 |
| 30S ribosomal protein S2 | gi|648400952 | WP_026092703.1 | -2.077 | 0.0015 |
| phosphoribosylamine—glycine ligase | gi|516101527 | WP_017532107.1 | -1.977 | 0.037 |
| thioredoxin | gi|516101608 | WP_017532188.1 | -1.935 | 0.0015 |
| membrane protein | gi|516101614 | WP_017532194.1 | -1.931 | < 0.00010 |
| 30S ribosomal protein S6 | gi|648400856 | WP_026092607.1 | -1.907 | 0.016 |
| hypothetical protein, partial | gi|516101417 | WP_017531997.1 | -1.737 | 0.011 |
| transcriptional activator protein | gi|516101552 | WP_017532132.1 | -1.585 | 0.02 |
| elongation factor Tu | gi|516101903 | WP_017532483.1 | -1.570 | 0.00038 |
| membrane protein | gi|516101809 | WP_017532389.1 | -1.439 | 0.024 |
| hypothetical protein | gi|516101930 | WP_017532510.1 | -1.392 | 0.012 |
| malate—CoA ligase subunit beta | gi|516101329 | WP_017531909.1 | -1.363 | 0.031 |
| peptidoglycan-associated lipoprotein | gi|516101767 | WP_017532347.1 | -1.322 | 0.014 |
| hypothetical protein | gi|516101366 | WP_017531946.1 | -1.170 | 0.039 |
| hypothetical protein | gi|516101286 | WP_017531866.1 | -1.000 | 0.011 |
| restriction endonuclease subunit S | gi|516101559 | WP_017532139.1 | -0.899 | 0.011 |
| hypothetical protein | gi|516101179 | WP_017531759.1 | -0.802 | 0.035 |
| molecular chaperone GroeL | gi|516101041 | WP_017531621.1 | -0.711 | 0.03 |
| hypothetical protein | gi|516101398 | WP_017531978.1 | -0.636 | 0.049 |
| succinyl-CoA synthetase subsunit alpha | gi|516101330 | WP_017531910.1 | Not found in CLas+ | 0.00014 |
| membrane protein | gi|648400895 | WP_026092646.1 | Not found in CLas+ | 0.00078 |
| elongation factor G | gi|648400891 | WP_026092642.1 | Not found in CLas+ | 0.0042 |
1 Annotation for corresponding protein/transcript from NCBI
2 Protein GI found in NCBI
3 Accession number for corresponding protein in NCBI
4 Log2 fold change generated by comparison of CLas+/CLas- spectral counts. A Log2 fold change cutoff of ±0.5 was applied for differential expression analysis
5 P-values were generated using a Fisher’s exact test and a p-value cutoff of <0.05 was applied