Table 2. Analytical ultracentrifugation of WT and mutant αIIb and β3 TM/CYT proteins.
αIIb | (P/L)50* | β3 | (P/L)50 |
---|---|---|---|
WT | 1.48 × 10-3 | WT | 2.25 × 10-2 |
G972N | 4.68 × 10-3 | G708N | 2.78 × 10-3 |
(P/L)50 corresponds to the protein/detergent ratio at which the fraction of monomeric protein is 50% and is a measure of its tendency to oligomerize