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. Author manuscript; available in PMC: 2018 May 13.
Published in final edited form as: Biochem Biophys Res Commun. 2017 Mar 28;486(4):951–957. doi: 10.1016/j.bbrc.2017.03.135

Figure 2. Decreased αSNAP expression attenuates Paneth cell differentiation.

Figure 2

(A) Dual-immunolabeling of a selective Paneth cell marker, lysozyme (red), and a general epithelial marker, β-catenin (green), in the ileac sections of wild-type and αSNAP-depleted homozygous hyh mice. Arrows indicate decreased lysozyme expression in the intestinal mucosa of αSNAP-depleted animals. (B) mRNA expression of Paneth cell markers, and regulators of Paneth cell differentiation in the whole ileac segments of these animals. Data is presented as mean ± SE (n = 6); *P<0.01 (unpaired Student’s t-test).