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. Author manuscript; available in PMC: 2017 Oct 19.
Published in final edited form as: Nature. 2017 Apr 19;545(7653):213–218. doi: 10.1038/nature22307

Figure 3. Total synthesis enabled by decarboxylative alkenylation.

Figure 3

All decarboxylative alkenylations were performed with in situ activation of the carboxylic acid. See SI for full synthetic details and schemes (a–h). LLS = longest linear sequence. [H] = reduction.