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. 2005 Jan 24;102(5):1661–1666. doi: 10.1073/pnas.0407183102

Fig. 1.

Fig. 1.

Erectile function in WT and NOS mutant mice. (a) Frequency of spontaneous erections before and after cavernous nerve stimulation (CNS). (b–d) Intracavernous pressure response relationships to CNS (0.25–6 V) (b) and to direct intracavernosal injection of the NO donor DEA/NO (0.03–1 μg/kg) (c) or the PDE5 inhibitor sildenafil citrate (0.3–30 μg/kg) (d). Data are represented as mean values with error bars representing the SEM. *, P < 0.001 for ANOVA; **, P < 0.05 for ANOVA WT or NOS1–/– vs. NOS3–/– or NOS1/3–/– in b. Comparison between WT and NOS1–/– was not significant in all groups studied. Comparison between NOS3–/– and NOS1/3–/– was not significant in all groups studied.