Table 4.
Day | Leucocyte (×109/L Healing |
Neutrophil (×109/L) Healing |
Lymphocyte (×109/L) Healing |
Platelets (×103/μl) Healing |
Fasting Blood Glucose (g/L) Healing |
C-Reactive Protein (mg/L) Healing |
||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Yes | No | Yes | No | Yes | No | Yes | No | Yes | No | Yes | No | |
0 | 9.15 ± 0.79 | 8.91 ± 0.61 | 5.87 ± 0.78 | 6.17 ± 0.47 | 2.24 ± 0.18 | 1.55 ± 0.17 | 269.11 ± 13.67 | 328.21 ± 39.03 | 4.07 ± 0.14 | 4.13 ± 0.26 | 29.61 ± 9.52 | 48.86 ± 11.78 |
3 | 8.90 ± 0.66 | 9.09 ± 0.78 | 5.89 ± 0.58 | 6.27 ± 0.59 | 2.05 ± 0.21 | 1.49 ± 0.16 | 263.25 ± 16.25 | 323.93 ± 41.51 | 4.06 ± 0.12 | 4.02 ± 0.26 | 26.92 ± 9.91 | 58.29 ± 14.10 |
7 | 8.70 ± 0.68 | 8.08 ± 0.77 | 5.53 ± 0.54 | 5.33 ± 0.66 | 2.10 ± 0.14 | 1.67 ± 0.17 | 290.43 ± 24.28 | 321.64 ± 39.41 | 4.05 ± 0.16 | 4.37 ± 0.27 | 17.92 ± 3.70 | 58.51 ± 16.42 |
14 | 9.85 ± 0.81 | 8.81 ± 0.79 | 6.49 ± 0.73 | 6.18 ± 0.64 | 2.34 ± 0.22 | 1.60 ± 0.17 | 303.15 ± 18.41 | 342.50 ± 34.62 | 4.20 ± 0.29 | 4.14 ± 0.30 | 29.45 ± 9.80 | 46.38 ± 13.50 |
30 | 9.41 ± 0.56 | 8.34 ± 0.74 | 6.25 ± 0.46 | 5.66 ± 0.63 | 2.27 ± 0.15 | 1.50 ± 0.14 | 312.62 ± 25.38 | 319.85 ± 42.94 | 3.95 ± 0.16 | 4.24 ± 0.24 | 10.19 ± 1.82 | 33.18 ± 9.39 |
Values are mean ± SEM for healing (Yes) and nonhealing (No). Analysis of peripheral blood was done at baseline and at 0, 3, 7, 14, and 30 days. Significant differences were found in the number of lymphocytes, and CRP between healing and nonhealing patients. Circulating C-reactive protein levels were significantly higher on day 3, 7, and 30 (p = 0.029, p = 0.009, and p = 0.010, respectively) in patients who did not heal. Lymphocyte counts were significantly lower on day 0, 3, 14, and 30 (p = 0.018, p = 0.036, p = 0.021, and p = 0.002, respectively) in the early stages of treatment, than those of patients that healed well (Group I).