Table 1.
Variables | Controls N=1468 |
Cases N=367 |
P value | ||
---|---|---|---|---|---|
| |||||
Demographics | n | % | n | % | |
Age, Mean (SD) (matching variable; for descriptive purposes only) | 84.8 | (8.2) | 84.8 | (8.2) | N/A |
Male (matching variable; for descriptive purposes only) | 340 | 23.2 | 85 | 23.2 | N/A |
White, Non-Hispanic | 1261 | 85.9 | 328 | 89.4 | 0.08 |
Health Status Factors | |||||
Cognitive function | 0.005 | ||||
intact | 466 | 31.7 | 85 | 23.2 | |
mild to moderate impairment | 865 | 58.9 | 243 | 66.2 | |
severe impairment | 137 | 9.3 | 39 | 10.6 | |
Walking aid use | 1384 | 94.3 | 336 | 91.6 | 0.051 |
Vision Impairment | 458 | 31.2 | 121 | 33.0 | 0.49 |
Wandering | 100 | 6.8 | 44 | 12.0 | 0.001 |
Parkinson’s disease | 72 | 4.9 | 26 | 7.1 | 0.10 |
Urinary incontinence | 795 | 54.2 | 191 | 52.0 | 0.47 |
Charlson Comorbidity Index excluding Dementia, Mean (SD) | 5.0 | (3.2) | 5.1 | (3.3) | 0.57 |
Use of other medications that may increase risk of falls/fracture/syncopea | 155 | 10.6 | 43 | 11.7 | 0.52 |
Number of medications at admission excluding those above b | 0.45 | ||||
0 | 271 | 18.5 | 56 | 15.3 | |
1–3 | 485 | 33.0 | 125 | 34.1 | |
4–8 | 556 | 37.9 | 150 | 40.9 | |
>=9 | 156 | 10.6 | 36 | 9.8 | |
CNS Medication Indications | 970 | 66.1 | 233 | 63.5 | 0.35 |
Anxiety | 317 | 21.6 | 86 | 23.4 | 0.47 |
Depression | 182 | 12.4 | 36 | 9.8 | 0.17 |
Seizure disorder | 78 | 5.3 | 22 | 6.0 | 0.60 |
Moderate/severe bodily pain | 562 | 38.3 | 122 | 33.2 | 0.07 |
Dementia medications | 234 | 15.9 | 58 | 15.8 | 0.95 |
Antidepressants other than TCAs, SSRIs, and SNRIs, or peripheral alpha blockers or skeletal muscle relaxants;
Excluding antidepressants, antiepileptics, antipsychotics, benzodiazepine receptor agonist hypnotics, opioid receptor agonists, peripheral alpha blockers, and skeletal muscle relaxants.
Abbreviations: CNS = central nervous system; MDS = Minimum Data Set; SD= standard deviation; SNRI = serotonin norepinephrine reuptake inhibitor; SSRI = selective serotonin reuptake inhibitor; TCA = tricyclic antidepressant