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. Author manuscript; available in PMC: 2018 Jun 1.
Published in final edited form as: J Am Geriatr Soc. 2017 Feb 2;65(6):1183–1189. doi: 10.1111/jgs.14759

Table 3.

Unadjusted and Multivariable Relationship between Standardized Daily Dose of CNS Medications and Serious Falls

Standardized Daily Dose Of CNS Medications Crude Odds Ratio
(95% CI)
Adjusted Odds Ratio a
(95% CI)
3+ 1.75 (1.31–2.33) 1.83 (1.35–2.48)
>0 – <3 0.87 (0.65–1.17) 0.85 (0.63–1.15)
0 Reference Reference
a

Conditonal logistic regression adjusted for race/ethnicity, cognitive function, walking aid use, vision impairment, wandering, Parkinson’s Disease, urinary incontinence, Charlson Comorbidity Index (excluding dementia), other medication use that may increase risk of falls/fractures/syncope, number of medications (excluding those above), and CNS medication indications (i.e., anxiety, depression, seizure disorder, moderate/severe bodily pain, and dementia medications)

Abbreviations; CI=confidence interval; CNS = central nervous system