Table 4.
ECog modelsa | ECog and cognition modelsb |
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---|---|---|---|---|
Independent variable | HR (95% CI) | p-value | HR (95% CI) | p-value |
Everyday Memory - informant | 2.0 (1.4–2.9) | <.001 | 1.8 (1.2–2.9) | .006 |
Everyday Language - informant | 1.5 (.9–2.4) | .12 | 1.3 (.7–2.4) | .46 |
Everyday Visuospatial - informant |
1.4 (.8–2.4) | .18 | 1.1 (.6–2.2) | .69 |
Everyday Planning - informant | 1.8 (1.1–3.1) | .02 | 2.0 (1.1–3.6) | .03 |
Everyday Organization - informant |
1.9 (1.3–2.8) | .001 | 1.9 (1.1–3.0) | .01 |
Everyday Divided Attention - informant |
1.7 (1.2–2.4)c | .001 | 1.7 (1.1–2.7) | .02 |
ECog Total Score - informant | 2.0 (1.3–3.2) | .002 | 1.9 (1.1–3.2) | .02 |
Everyday Memory - self | 1.9 (1.3–2.6) | <.001 | 1.6 (1.1–2.4) | .02 |
Everyday Language - self | 1.8 (1.2–2.7) | .003 | 1.6 (.9–2.6) | .10 |
Everyday Visuospatial - self | 1.8 (1.1–2.9) | .03 | 1.6 (.9–2.8) | .10 |
Everyday Planning - self | 1.8 (1.1–3.0) | .01 | 1.6 (.8–3.0) | .17 |
Everyday Organization - self | 1.9 (1.2–2.9) | .003 | 1.4 (.8–2.4) | .21 |
Everyday Divided Attention - self | 1.6 (1.1–2.3) | .006 | 1.7 (1.1–2.5) | .01 |
ECog Total Score - self | 2.3 (1.4–3.6) | <.001 | 1.9 (1.1–3.4) | .03 |
Note: ECog = Everyday Cognition Scales; CI = confident interval; HR = hazard ratio.
Model adjusted for age, education and baseline ECog domain or total score.
Model adjusted for age, education, baseline ECog domain or total score, and cognitive functioning (memory and executive functions)
The assumption of proportional hazards is not met in this model (p=.03). When an interaction between baseline Everyday Divided Attention and logarithm of time is included in the model, the estimated hazard ratio is higher at early time points and lower at later time points (i.e., the hazard ratio decreases over time).